Background Practice guidelines recommend using panitumumab in combination with chemotherapy to treat KRAS wild-type (WT) metastatic colorectal cancer (mCRC) patients where it was shown to significantly extend progression-free survival (PFS)…
This exclusive initiative, spearheaded by Biogen (https://www.biogen.com/) and HLTH Inc. (https://hlth.com/), aims to accelerate innovation in the field of rare neuromuscular diseases, with a strong focus on early diagnosis and…
Background: Diagnosis of hereditary angioedema (HAE) poses challenges because of its rarity and its overlapping symptoms with allergic and gastrointestinal conditions, resulting in misdiagnosis. Objective: We developed a predictive score…
Success Story Topazium: AI for More Human-Centered Care By José Luis Diez, independent consultant and advisor in information technology, digital transformation, and digital health; business angel for startups. The company…
The increasing availability of massive genetic sequencing data in the clinical setting has triggered the need for appropriate tools to help fully exploit the wealth of information these data possess.…
Madrid. Topazium has been honored in the IV edition of the Ennova Health Awards organized by Diario Médico and Correo Farmacéutico in the big data and artificial intelligence category. …
ABC – Laura Montero Carretero – 03/11/2024 The vast potential of the multiplier effect of AI algorithms is opening up a new economic opportunity, one that global giants have already…
Introduction: Ultrasound (US) is widely used for diagnosing liver disease, particularly cirrhosis, with key signs including liver shape irregularity and echostructure. The classification of liver parenchyma as smooth or coarse,…
Madrid, September 12, 2024. Spain has unique conditions for the development of innovative medicines and a leading role, not only in Europe but globally, due to the excellence of its…
The Spanish company specialized in artificial intelligence (AI), Topazium, in collaboration with Biomakers, has presented at a meeting of the prestigious American Society of Clinical Oncology how AI can accelerate…
San Francisco, CA – July 17th, 2024 – BIOMAKERS, a Precision Medicine & Biotech Company that supports data-driven Drug Development globally, and TOPAZIUM, an AI-driven healthtech company specializing in drug…
The magazine Emprendedores has organised a second meeting to discuss the impact of artificial intelligence (AI) on business. The aim was for the meeting to be practical for all attendees,…
On June 11, Topazium presented at Madrid Innovation Lab (MIL; https://milmadrid.es/) its project HealthGuard, winner of the challenge “Mechanisms for Predicting and Controlling Chronic Diseases” at the 2023 AI and…
SkinGuard is a computer-vision smartphone-based application utilising cutting-edge machine learning technologies to identify malignant skin lesions with an accuracy above 96%. It was fully developed and implemented by Topazium and…
Background: The advent of drugs targeting the PD-1/PD-L1 axis has revolutionized NSCLC treatment. Although promising, individual responses to these therapies can vary among individuals, and research is ongoing to better…
Background: Predicting life expectancy in prostate cancer patients is particularly difficult as different clinical factors significantly influence clinical outcome. Here we have developed MOSPROC, a simplified mortality predictive score to…
In an era of technological uncertainty, artificial intelligence (AI) emerges as a revolutionary tool capable of transforming multiple sectors, including medicine. However, it is crucial to understand its role as…
Two machine learning frameworks developed in Topazium, GFPrint™ and PredLung™, have been used to extract important information from cancer patients, in particular from lung cancer patients, that may serve to…
Some analyses of last year’s progress in AI-powered drug discovery indicate that none of the molecules fully generated by artificial intelligence (AI) were taken from discovery through clinical development. Although…
The increasing availability of massive genetic sequencing data in the clinical setting has triggered the need for appropriate tools to help fully exploit the wealth of information these data possess.…
Madrid, February 21, 2024. Topazium, a company specializing in the application of artificial intelligence in the field of biomedicine, has been awarded the 2023 Artificial Intelligence and Advanced Technologies Award…
In the digital age, artificial intelligence (AI) has emerged as a transformative force across numerous sectors, including the food industry. Notably, AI has become a key tool in detecting and…
According to data from the Argentinean Society of Dermatology (SAD), 40% of Argentines claim to protect themselves from the sun occasionally and more than 60% do not renew sun protection…
Revista Emprendedores have searched for the most innovative projects of 2023 in the Spanish market to produce the 8th Emprendedores List of innovative startups. Spanish, innovative and very young. We…
Artificial intelligence brings to medicine a different and more complete data analysis system than those used to date. In the latest episode of KREAB Fika Café, Carlos M. Galmarini reflected…
Artificial intelligence (AI) has become a promising tool for the discovery of pharmaceuticals, as it can enhance the probabilities of success and adds greater precision, speed and profitability to a…
NutriGuard™, Topazium’s AI tool to harness the healthy benefits of food, has been selected as a finalist for the Awards category: BEST HEALTH DATA-DRIVEN INNOVATION at #DES2023*! NutriGuard™ purpose is to…
Drug discovery is a costly process affected by a high attrition rate. The huge investment from pharma industry in past years has generated a vast wealth of information in the…
AI has become a much more common element of medical devices in the past few years, with submissions increasing rapidly over the last 3 years. This significant growth is being…
If we asked the most famous artificial intelligence (AI) based chat today about the role that data analysis plays in everyday clinical practice, it would respond that it is increasingly…
NutriGuard is a machine learning framework designed and developed by Topazium to harness the potential of food components for promoting and preserving health. It is inspired by the need to understand…
Artificial intelligence (AI) is a technology well suited for dealing with large amounts of information and has long been considered a promising tool in drug discovery. It has made steady…
BACKGROUND Machine learning (ML) tools are suitable to dive vast amounts of clinical and genetic information in order to identify genetic biomarkers of worse survival and potential new molecular targets.…
Introduction. Diagnostic errors between nevic lesions and skin tumors are frequent for non-specialist physicians. Therefore, there is a need to create a simple and practical tool based on artificial intelligence…
Drug discovery is a lengthy and costly process affected by a high attrition rate. The revolution in experimental sciences brought about by HTE, cloud labs and lab automation should represent…
En un mundo en constante cambio y evolución como el nuestro, pocos métodos o doctrinas pueden tener el honor de permanecer vigentes durante más de 2.000 años. Uno de estos…
Globant and Topazium join to create new paradigms in drug discovery, clinical research, diagnostics, and well-being MADRID – September 27, 2022 – Globant (NYSE: GLOB), a digitally native company focused…
Background: Treatment with DP improves survival in mCRCP but is associated with significant toxicity. The question remains as to whether the improved survival is worth the toxicity risk. In this…
Background: The optimal time to begin therapy in mCRPC patients who have either no, or minimal symptoms is not defined yet. Estimating prognosis of these patients can avoid undertreatment or…
Background: Practice guidelines recommend using P to treat K-Ras WT mCRC patients where it was shown to significantly extend overall survival (OS). Still, a proportion of patients will not achieve…
Background: To understand the transcriptomic response to SARS-CoV-2 infection, is of the utmost importance to design diagnostic tools predicting the severity of the infection. Methods: We have performed a deep…
Visit our booth at SLAS Europe 2022 and see how our AI systems can improve your drug discovery programs!
Topazium has been selected for the final Innovative AveNEW lineup at #SLASEurope22 in Dublin. Very honored for this recognition and eager to share out latest advances in such a renowned forum within…
We are very proud to announce that we are one of the seven companies selected in the Start-ups Meet Healthcare Providers program. The programme matches the start-ups behind the innovative…
We have been labeled as “Innovative SME” from the Ministry of Science and Innovation.
Despite their wide differences (1), most theories about cancer proposed during the past century agree that cancer is a biological nonsense for the organism in which it originates since cancer…
CAREERS Open positions. We are expanding our team in Madrid. If you’re looking for a new challenge which will fulfil and inspire you, join us: SENIOR ARTIFICIAL INTELLIGENCE MANAGER…
We are very proud to share that we have been awarded by the Centre for the Development of Industrial Technology (CDTI) with a NEOTEC 2021 grant. This public support will…
Background: Patients with K-RAS wild-type (WT) metastatic colorectal cancer (mCRC) are currently considered the optimal candidates for upfront treatment with combinations of chemotherapy and EGFR inhibitors. These combinations significantly extend…
Background: Synthetic fingerprints integrate clinical data within computational models allowing the identification of particular clinical subpopulations at a given moment. We here describe a deep learning strategy to detect super-responder…
Background: Predicting the clinical course of metastatic disease remains a key challenge in CRC. Estimating prognosis of these late-stage patients can avoid undertreatment or overtreatment and also guide the follow-up…
This study evaluated whether deep learning frameworks trained in large datasets can help non-dermatologist physicians improve their accuracy in categorizing the seven most common pigmented skin lesions. Open-source skin images…
The goal of all medical activity is to preserve health in fit people, and to restore the sick into a state of complete physical, mental and social wellbeing. In an…
Although highly successful, the medical R&D model is failing at improving people’s health due to a series of flaws and defects inherent to the model itself. A new collective intelligence,…
A medida que se acelera y agrava la situación sanitaria de Covid-19, es inminente la utilización de tecnologías que permitan no sólo frenar la propagación del virus sino también detectarlo…
The ultimate goal of all medical activity is to restore patients to a state of complete physical, mental, and social wellbeing. In cancer, it is assumed that this can only…
COVID-19 can exponentially precipitate life-threatening emergencies as witnessed during the recent spreading of a novel coronavirus infection which can rapidly evolve into lung collapse and respiratory distress (among other various…
Artificial intelligence can be a key tool in the context of assisting in the diagnosis of dermatological conditions, particularly when performed by general practitioners with limited or no access to…
A new partner in the largest telemedicine network in Latin America: Topazium Artificial Intelligence and Telmed shares the same vision: uniting against COVID-19 by providing a high-quality, collaborative and technological…
Skin lesions are one of the most common human diseases and affect millions of people worldwide 1. Moreover, its prevalence will raise every year due to the aging of the…
Around 200 billion US dollars are invested every year in medical research worldwide (1). The result of this collective effort has been astonishing: In just 100 years, life expectancy rocketed…
Moving Towards a Collective Intelligence “The physician should convert or insert wisdom into medicine and medicine to wisdom.” (Hippocrates, physician, 460 BC – 370 BC). Modern medicine is based upon…
