PROCC: a predictive score to identify KRAS wild type metastatic colorectal cancer patients who are likely to benefit from panitumumab treatment

Background Practice guidelines recommend using panitumumab in combination with chemotherapy to treat KRAS wild-type (WT) metastatic colorectal cancer (mCRC) patients where it was shown to significantly extend progression-free survival (PFS) and overall survival (OS). Still, a proportion of patients will not achieve this goal. We propose a simplified predictive score to identify patients who are…

Success Story : Topazium, AI for More Human-Centered Care

Success Story Topazium: AI for More Human-Centered Care  By José Luis Diez, independent consultant and advisor in information technology, digital transformation, and digital health; business angel for startups. The company incorporates machine learning mechanisms to identify, for each patient’s profile, the combination of foods and ingredients that can best contribute to a healthy life.  …

GFPrint™: A machine learning tool for transforming genetic data into clinical insights

The increasing availability of massive genetic sequencing data in the clinical setting has triggered the need for appropriate tools to help fully exploit the wealth of information these data possess. GFPrint™ is a proprietary streaming algorithm designed to meet that need. By extracting the most relevant functional features, GFPrint™ transforms high-dimensional, noisy genetic sequencing data…

LivGuard, a deep neural network for cirrhosis detection in liver ultrasound (USD)

Introduction: Ultrasound (US) is widely used for diagnosing liver disease, particularly cirrhosis, with key signs including liver shape irregularity and echostructure. The classification of liver parenchyma as smooth or coarse, indicative of chronic liver disease, is subjective and dependent on operator experience. To address this, we introduce LivGuard, a deep learning binary classifier designed to…

BIOMAKERS and TOPAZIUM Unveil Groundbreaking AI Collaboration to Enhance NSCLC Immunotherapy

San Francisco, CA – July 17th, 2024 – BIOMAKERS, a Precision Medicine & Biotech Company that supports data-driven Drug Development globally, and TOPAZIUM, an AI-driven healthtech company specializing in drug discovery and human wellbeing, have announced the results of their innovative collaborative project. This partnership showcases the power of AI systems in leveraging real-world DNA…

“We live longer, but we want to live better”

On June 11, Topazium presented at Madrid Innovation Lab (MIL; https://milmadrid.es/) its project HealthGuard, winner of the challenge “Mechanisms for Predicting and Controlling Chronic Diseases” at the 2023 AI and Advanced Technologies Awards. After a few words of welcome, Patricia Sarasola, Head of the Innovation Department of the Madrid City Council, emphasized the accessibility of…