Development and validation of MOSPROC, an easily applicable predictive score of mortality for patients with prostate cancer

Medicine, Oncology, TopaziumLeave a comment

Background: Predicting life expectancy in prostate cancer patients is particularly difficult as different clinical factors significantly influence clinical outcome. Here we have developed MOSPROC, a simplified mortality predictive score to identify prostate cancer patients at high risk of mortality. Methods: The training set (TRS) (n=2,035) included metastatic Castration Resistant PC (mCRPC) patients from 4 randomized…

Ethics or Atics? The role of artificial intelligence in medicine

Collective Intelligence, Medicine, Publications, TopaziumLeave a comment

In an era of technological uncertainty, artificial intelligence (AI) emerges as a revolutionary tool capable of transforming multiple sectors, including medicine. However, it is crucial to understand its role as a complement rather than a substitute for human intelligence and quality, while maintaining the legacy of the Hippocratic method. The era of Artificial Intelligence (AI)…

GFPrint and PredLung nominated finalists in the AstraZeneca’s BeLung Innovation challenge

Press release, R&D, TopaziumLeave a comment

Two machine learning frameworks developed in Topazium, GFPrint™ and PredLung™, have been used to extract important information from cancer patients, in particular from lung cancer patients, that may serve to design better therapies, generate virtual biomarker signatures and predict patient outcomes. Three case studies are presented, focused on i) the discovery of potential novel targets…

GFPrint™: a machine learning tool for transforming genetic data into clinical insights

Genetics, Oncology, Publications, R&DLeave a comment

The increasing availability of massive genetic sequencing data in the clinical setting has triggered the need for appropriate tools to help fully exploit the wealth of information these data possess. GFPrint™ is a proprietary streaming algorithm designed to meet that need. By extracting the most relevant functional features, GFPrint™ transforms high-dimensional, noisy genetic sequencing data…

Topazium Receives the 2023 Artificial Intelligence and Advanced Technologies Award from the Madrid City Council for HealthGuard™

Press release, WellnessLeave a comment

Madrid, February 21, 2024. Topazium, a company specializing in the application of artificial intelligence in the field of biomedicine, has been awarded the 2023 Artificial Intelligence and Advanced Technologies Award by the Madrid City Council for HealthGuard™, a machine learning framework designed and developed by the company that utilizes the most advanced AI technologies to…